| Course | DNRS 6630 Psychopharmacologic Approaches to Treatment of Psychopathology |
|---|---|
| Week | Week 10 |
| Paper type | Integrated case paper |
| Length | About 1,020 words, 6 pages |
| Format | APA 7 student paper |
| School | Walden University |
| Program | Doctor of Nursing Practice (DNP) |
| Updated | October 2026 |
Free sample paper for DNRS 6630 Week 10
Integrated Case Paper: A Second Episode of Depression With Anxious Distress in a 38-Year-Old Night-Shift Worker
Student Name
College of Nursing, Walden University
DNRS 6630: Psychopharmacologic Approaches to Treatment of Psychopathology
Instructor Name
Month Day, Year
Integrated Case Paper: A Second Episode of Depression With Anxious Distress in a 38-Year-Old Night-Shift Worker
Presentation
The case is assembled for teaching, not observed. Known facts are numbered so later sections can point to them. P1: a 38-year-old man, second episode of major depression, 10 weeks in. P2: PHQ-9 score 19 (Kroenke et al., 2001). P3: marked worry, restlessness, and a sense that something bad will happen, meeting the anxious distress specifier. P4: works rotating night shifts as a warehouse supervisor. P5: AUDIT-C score of 5, mostly drinks after night shifts to sleep (Bush et al., 1998). P6: first episode 4 years ago treated with a serotonin reuptake inhibitor, with partial response; he stopped after 5 months because of sexual side effects. P7: no suicidal intent; passive thoughts on the C-SSRS screen. P8: prefers not to take "anything that makes me a zombie at work."
Inferred, and marked as such. I1: his drinking may be worsening his sleep and mood rather than only responding to them. I2: his previous partial response may reflect early discontinuation as much as the drug.
Formulation
His current episode is shaped by three interacting factors. Circadian disruption from rotating night shifts (P4) impairs sleep and may deepen low mood and anxiety. Alcohol used as a sleep aid (P5) gives short-term sedation but fragments later sleep, which feeds the anxious distress in P3; this is inference I1 and is testable. His treatment history (P6) shows a class that helped partially and a side effect that ended treatment, which tells us more about what he will tolerate than about what will work. His priority in P8 is a constraint on any plan, not a preference to be overridden.
The formulation also has protective elements that the plan should use. He recognized the pattern of this episode early, at 10 weeks rather than months (P1), he came in on his own, and his statement in P8 shows he is thinking about staying well at work rather than avoiding treatment. His passive thoughts of death (P7) are a risk to be monitored, but his lack of intent and his engagement mean the plan can be built on collaboration rather than on supervision. These strengths explain why a plan that asks him to change his drinking and his sleep routine is realistic.
The Decision
The decision is to combine cognitive behavioral therapy, with a sleep component adapted to shift work, and an antidepressant from a class with a different side-effect profile from the one he stopped (P6). The combination draws on the network meta-analysis showing combined treatment more effective than either alone in adult depression (Cuijpers et al., 2020). The choice of a different class draws on the appraisal work earlier in the term: the STAR*D design tested switching to a different agent after an inadequate first treatment (Rush et al., 2004), and he resembles its enrolled population more closely than the older woman we appraised it for, since he is under 75, an outpatient, and without medical exclusions. Among antidepressants, several classes show similar efficacy with differing acceptability (Cipriani et al., 2018), which makes tolerability, and specifically his experience in P6 and his priority in P8, the deciding factor. The alcohol in P5 is addressed directly as part of treatment, not left for later.
The therapy component is adapted to his schedule. Sessions are booked at the start of his days off rather than weekly on fixed days, and the sleep component focuses on a consistent anchor sleep period after night shifts, light exposure timing, and replacing alcohol as a sleep aid with a wind-down routine. These adaptations follow directly from P4 and P5; a standard weekly program would collide with his rota within a month. The antidepressant's timing of dose will be set around his main sleep period rather than around the clock, and he is asked to report if a change in shift pattern upsets it.
Alternatives Set Aside
Psychotherapy alone was treated as a serious option, not a formality. It fits his wish to avoid sedation (P8), and cognitive behavioral therapy is effective for depression (Cuijpers et al., 2020). It was set aside as the sole treatment because his severity (P2), his anxious distress (P3), and his passive thoughts of death (P7) argue against waiting weeks for therapy alone to take effect, and because his shift pattern will make weekly sessions irregular. It remains half of the plan.
Restarting the class he took before was also considered, since it helped partly (P6). It was set aside because the side effect that ended treatment is likely to recur and end it again, and a plan he stops at month 5 does not serve him.
Monitoring
The PHQ-9 is repeated in the second, fourth, eighth, and twelfth weeks, with the C-SSRS screen at every contact because of P7. The AUDIT-C is repeated at week 4 to test inference I1. Side effects are asked about specifically, including sexual effects, because they ended treatment last time (P6). Adherence is recorded as missed days in the last 7 (Stirratt et al., 2015). Sleep timing is logged by him across shift changes.
Contingency
If his PHQ-9 improves by under 20% at week 4, or by under half at the eighth week, adherence and alcohol are reviewed first, since either could explain it, and then the plan changes by adjusting within the class, switching again, or intensifying therapy. If sexual side effects appear, they are discussed before he stops, not after. Any escalation in suicidal thinking triggers same-day assessment.
Limitations
Three questions remain unresolved. Whether his alcohol use is driving his mood or following it (I1) cannot be settled until he has reduced drinking for several weeks. Whether his earlier partial response reflected the drug or the early stop (I2) cannot be known now and matters for how much weight P6 deserves. And the evidence behind the decision comes from trials in which shift workers are rarely described, so the effect of rotating nights on his response is unmeasured. The plan is built to learn the first answer within a month; the other two may stay open.
References
Bush, K., Kivlahan, D. R., McDonell, M. B., Fihn, S. D., & Bradley, K. A. (1998). The AUDIT alcohol consumption questions (AUDIT-C): An effective brief screening test for problem drinking. Archives of Internal Medicine, 158(16), 1789-1795. https://doi.org/10.1001/archinte.158.16.1789
Cipriani, A., Furukawa, T. A., Salanti, G., Chaimani, A., Atkinson, L. Z., Ogawa, Y., Leucht, S., Ruhe, H. G., Turner, E. H., Higgins, J. P. T., Egger, M., Takeshima, N., Hayasaka, Y., Imai, H., Shinohara, K., Tajika, A., Ioannidis, J. P. A., & Geddes, J. R. (2018). Comparative efficacy and acceptability of 21 antidepressant drugs for the acute treatment of adults with major depressive disorder: A systematic review and network meta-analysis. The Lancet, 391(10128), 1357-1366. https://doi.org/10.1016/S0140-6736(17)32802-7
Cuijpers, P., Noma, H., Karyotaki, E., Vinkers, C. H., Cipriani, A., & Furukawa, T. A. (2020). A network meta-analysis of the effects of psychotherapies, pharmacotherapies and their combination in the treatment of adult depression. World Psychiatry, 19(1), 92-107. https://doi.org/10.1002/wps.20701
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001). The PHQ-9: Validity of a brief depression severity measure. Journal of General Internal Medicine, 16(9), 606-613. https://doi.org/10.1046/j.1525-1497.2001.016009606.x
Rush, A. J., Fava, M., Wisniewski, S. R., Lavori, P. W., Trivedi, M. H., Sackeim, H. A., Thase, M. E., Nierenberg, A. A., Quitkin, F. M., Kashner, T. M., Kupfer, D. J., Rosenbaum, J. F., Alpert, J., Stewart, J. W., McGrath, P. J., Biggs, M. M., Shores-Wilson, K., Lebowitz, B. D., Ritz, L., . . . STAR*D Investigators Group. (2004). Sequenced treatment alternatives to relieve depression (STAR*D): Rationale and design. Controlled Clinical Trials, 25(1), 119-142. https://doi.org/10.1016/S0197-2456(03)00112-0
Stirratt, M. J., Dunbar-Jacob, J., Crane, H. M., Simoni, J. M., Czajkowski, S., Hilliard, M. E., Aikens, J. E., Hunter, C. M., Velligan, D. I., Huntley, K., Ogedegbe, G., Rand, C. S., Schron, E., & Nilsen, W. J. (2015). Self-report measures of medication adherence behavior: Recommendations on optimal use. Translational Behavioral Medicine, 5(4), 470-482. https://doi.org/10.1007/s13142-015-0315-2
What the DNRS 6630 Week 10 instructions ask for
In the tenth week DNRS 6630 typically asks for an integrated case paper that draws together assessment, diagnosis, treatment selection, monitoring and follow-up for one patient. The prompt often requires a formulation that explains why the patient presents as they do, a decision with alternatives considered, and a plan for nonresponse. Integration is usually the word in the rubric, so sections should refer to each other. Expect a longer APA 7 paper of six to eight pages citing guidelines and comparative evidence. Earlier assignments can sometimes be built on if the work is extended. A limitations section is commonly expected. Some sections ask that a nonpharmacological option be weighed alongside medication. The patient's own goals, such as staying on nights or getting back to days, often belong in the formulation too.
Inside the DNRS 6630 Week 10 example
Seven sections and a habit of internal reference running through all of them. The presentation reports what is known and marks separately what is inferred, a separation few papers bother to make. The formulation explains rather than restates, and every explanatory claim points back at a specific line in the presentation above it. The decision section commits, and its justification draws on appraisal work from earlier in the term rather than on a fresh literature search. Two alternatives appear with the particular reason each was set aside, and one of them is a non-pharmacologic option treated seriously instead of mentioned in passing. Monitoring and contingency follow the format the course has been building. The case is assembled rather than observed.
DNRS 6630 Week 10 rubric: what earns full marks
Integration is the word in most rubrics for this week and markers test it by checking whether sections speak to one another. A paper reading as separate assignments joined together loses the largest single share, and the tell is a formulation that never cites the presentation above it. The alternatives section is second, where dismissive treatment of a real option costs analysis credit. Monitoring inconsistent with the stated decision is caught reliably, since the two sit close enough to compare. Limitations written generically collect almost nothing. Formatting and citation weight is higher here than anywhere else in the course because the document is the term's largest, and a reference list that has drifted from the body is visible immediately at this length.
DNRS 6630 Week 10 help: mistakes that cost marks
The usual way this paper falls short is reading as separate assignments stapled together, with a formulation that never informs the decision. Point back to specific facts as the example does with its numbered list. Another mistake is setting aside alternatives in a single line; give each a reason tied to the patient. Writers also forget the work schedule, though night shifts affect sleep, dosing time and follow-up. Keep the monitoring specific in measure and interval. Avoid adding new facts in the discussion that were not in the presentation. Include psychotherapy as a real option, not a footnote. Close the limitations section with what you would want to know at the next visit. Finally, keep the PHQ-9 score, the week count and the AUDIT-C result identical in every section that mentions them.
Get a DNRS 6630 Week 10 example written to your instructions
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DNRS 6630 Week 10 questions, answered
Can earlier assignments be reused inside this paper?
Most sections expect the thinking to carry forward and some explicitly permit reusing your own earlier work, but self-plagiarism rules differ by classroom and are worth reading before pasting anything. The example reuses conclusions and restates the assumptions behind them rather than lifting paragraphs, which is the safer approach and usually the stronger one.
How does a paper show integration rather than claim it?
By pointing. A formulation sentence that names the presentation line it rests on demonstrates integration in a way that no summary paragraph can. The example does this perhaps a dozen times, and the cross-references are short enough not to interrupt the reading. Markers looking for integration are looking for exactly those pointers.
Is a non-pharmacologic option required in the comparison?
Prompts vary, but including one usually strengthens the paper whether or not it is required. A defended medication decision looks considerably better beside an option that was weighed and set aside for stated reasons. Where a section requires it, the requirement is normally that the option receive real evidence treatment rather than a courteous mention.
Where can I find a free DNRS 6630 Week 10 sample paper?
This page holds the full night-shift worker case paper, from the numbered presentation through formulation, decision, alternatives, monitoring and limitations.
Who is the patient in the DNRS 6630 Week 10 paper?
A composite 38-year-old night-shift worker ten weeks into a second episode of major depression with anxious distress, with a PHQ-9 of 19.