| Course | NRNP 6566 Advanced Care of Adults in Acute Settings I |
|---|---|
| Week | Week 7 |
| Paper type | Acute kidney injury workup |
| Length | About 830 words, 6 pages |
| Format | APA 7 student paper |
| School | Walden University |
| Program | MSN Adult-Gerontology Acute Care Nurse Practitioner (AGACNP) |
| Updated | October 2026 |
Free sample paper for NRNP 6566 Week 7
Acute Kidney Injury Workup: A Creatinine 2.6 Times Baseline After Four Days of Diarrhea, Sorted by Compartment
Student Name
College of Nursing, Walden University
NRNP 6566: Advanced Care of Adults in Acute Settings I
Instructor Name
Month Day, Year
Acute Kidney Injury Workup: A Creatinine 2.6 Times Baseline After Four Days of Diarrhea, Sorted by Compartment
Finding the Baseline
Composite case. A 77-year-old retired seamstress admitted with 4 days of watery diarrhea, 6 to 8 episodes a day, after her grandchildren visited with a stomach virus. Creatinine today: 2.3 mg/dL. Baseline: 0.9 mg/dL, from an outpatient panel 5 months ago, consistent with three earlier values over 2 years between 0.8 and 0.9. The baseline is recent, repeated, and from a period of stable health, which makes it trustworthy.
Staging by KDIGO
The KDIGO criteria define acute kidney injury by a rise in creatinine of 0.3 mg/dL within 48 hours, a rise to 1.5 times baseline within 7 days, or low urine output, and stage it by the size of the rise (Khwaja, 2012). Her creatinine is 2.6 times her baseline, which is stage 2 (2.0 to 2.9 times baseline). Urine output over the first 6 hours in the unit: 150 mL, about 0.4 mL/kg per hour at her weight of 62 kg, which meets the urine criterion for stage 1 so far; the urine criterion for stage 2 requires that low rate to last 12 hours, so the creatinine, not the urine output, sets her stage today.
History: Intake, Losses, Contrast, Medications
Intake: sips of tea and crackers for 3 days; she stopped eating meals. Losses: diarrhea as above; no vomiting. Recent contrast: CT of the abdomen with intravenous contrast 4 days ago, in the emergency department, for abdominal cramps on the first day of diarrhea; creatinine that day was 1.1 mg/dL.
Medications, every one with renal effects noted: losartan 50 mg daily, taken through the illness; chlorthalidone 12.5 mg daily, taken; metformin 500 mg twice daily, taken; omeprazole 20 mg daily for 4 years. Over the counter, asked about by name: no ibuprofen or naproxen; acetaminophen twice; loperamide once.
Volume on Examination
Lying heart rate 86, blood pressure 108/62; standing heart rate 110, blood pressure 94/58, with lightheadedness but able to stand. Axillae dry; tongue dry and furrowed; mucous membranes dry. Jugular venous pressure not visible at 30 degrees. No edema. Lungs clear.
Bedside volume signs are individually weak. In a systematic review, a postural pulse rise of 30 beats per minute or more, or dizziness so severe that upright vital signs cannot be measured, was needed to diagnose large blood loss, while a dry axilla supported hypovolemia in patients with vomiting, diarrhea, or poor intake, and moist mucous membranes with an unfurrowed tongue argued against it (McGee et al., 1999). She has a postural rise of 24, below the stronger threshold, but a dry axilla, a dry furrowed tongue, a flat neck vein, and a history of large losses. Several weak signs pointing the same way, with a matching history, are more convincing than any one of them.
Bladder: bladder scan after voiding, 80 mL; no suprapubic fullness.
Urine Studies and Imaging, as Findings
Urinalysis: specific gravity 1.025; no protein, blood, or leukocytes; microscopy with occasional hyaline casts, no granular or muddy brown casts, no white cell casts, no red cell casts. Fractional excretion of urea 24%, used rather than fractional excretion of sodium because she takes a thiazide-like diuretic. No renal ultrasound yet.
Three Compartments
Prerenal, leading: large gastrointestinal losses with poor intake, postural changes, dry axilla and tongue, concentrated urine, a bland sediment with only hyaline casts, and a fractional excretion of urea below 35%. Her losartan and chlorthalidone, continued through 4 days of diarrhea, removed her kidneys' ability to compensate.
Intrinsic, possible but not leading: acute tubular injury can follow prolonged prerenal injury, but there are no granular casts; contrast was given when her creatinine was still 1.1, and the prerenal findings better explain the rise; acute interstitial nephritis from omeprazole is possible after long use, but there is no rash, fever, pyuria, or white cell casts.
Postrenal, unlikely: post-void residual of 80 mL; no history of hydronephrosis, recurrent urinary infections, or obstructive symptoms. In a risk framework derived from inpatients with kidney injury, patients with prerenal injury, nephrotoxic drug exposure, and no history of hydronephrosis or obstruction were in the group least likely to have hydronephrosis on ultrasound (Licurse et al., 2010). Renal ultrasound is therefore deferred, with a trigger: order it if creatinine has not begun to fall after 48 hours of volume repletion.
Medications as a Plan Category
Hold losartan and chlorthalidone until creatinine returns toward baseline and she is eating and drinking; restart losartan first. Hold metformin while creatinine is elevated. Continue omeprazole for now but reassess the indication at discharge. No NSAIDs. Avoid further contrast unless essential. Review every new order for renal dosing.
Other plan: isotonic balanced crystalloid, 1 liter over 2 hours, then 100 mL an hour, reassessed every 6 hours against urine output, postural vital signs, and lung examination; basic metabolic panel twice daily for potassium and creatinine; stool testing for pathogens given the duration; oral intake encouraged as diarrhea settles. Her daughter, her contact, was updated with her permission.
References
Khwaja, A. (2012). KDIGO clinical practice guidelines for acute kidney injury. Nephron Clinical Practice, 120(4), c179-c184. https://doi.org/10.1159/000339789
Licurse, A., Kim, M. C., Dziura, J., Forman, H. P., Formica, R. N., Makarov, D. V., Parikh, C. R., & Gross, C. P. (2010). Renal ultrasonography in the evaluation of acute kidney injury: Developing a risk stratification framework. Archives of Internal Medicine, 170(21), 1900-1907. https://doi.org/10.1001/archinternmed.2010.419
McGee, S., Abernethy, W. B., & Simel, D. L. (1999). The rational clinical examination: Is this patient hypovolemic? JAMA, 281(11), 1022-1029. https://doi.org/10.1001/jama.281.11.1022
Reading the NRNP 6566 Week 7 instructions
Week 7 of NRNP 6566 often asks for a workup of acute kidney injury in a hospitalized adult. You establish a baseline creatinine, stage the injury, take a focused history of intake, losses, exposures and medications, assess volume, interpret urine studies and imaging, sort causes by compartment and plan treatment including medication changes. Faculty deduct immediately for a missing baseline. Cite KDIGO in APA 7. Fluid volumes and rates may be omitted in favor of reasoning. Nephrotoxic drugs should be listed and acted on. More than one cause can coexist, and the workup should say so. NRNP 6566 faculty also want urine sodium or fractional excretion interpreted with its limits, and the kidney ultrasound result stated as a finding.
How this NRNP 6566 Week 7 example is built
Organized around three anatomic compartments, the workup runs about three pages. A baseline paragraph states where the prior creatinine came from and how old it is, then applies KDIGO staging to show the size of the change. The history records intake, losses, recent contrast, and every medication with renal effects, including over-the-counter pain relievers. The examination concentrates on volume: mucous membranes, jugular venous pressure, orthostatic change, edema, and a bladder assessment for retention. Urine studies and imaging are reported as findings. The differential then sorts candidate causes into prerenal, intrinsic and postrenal groups, and the example argues which group the evidence favors while keeping one alternative open. The plan explains volume strategy, holding or adjusting implicated drugs, dose review for renally cleared medications, monitoring, and when nephrology input would be sought. No chart supplied her details.
NRNP 6566 Week 7 rubric: what earns full marks
A workup without a baseline tends to lose points before its reasoning is even read, since the grader cannot judge severity. Next comes the frame: causes listed in no particular order, rather than sorted into compartments with evidence, look unexamined. Volume status asserted from a single finding, such as dry mucous membranes alone, draws comment because bedside volume signs are individually weak and the rubric expects several. Medication review is the quietest loss; a history recording the prescribed regimen but not the over-the-counter pain reliever misses a common contributor. Plans addressing the leading cause and ignoring a second contributor lose the evaluation line. Small deductions follow from urine findings reported without interpretation and from staging presented without its criteria.
NRNP 6566 Week 7 help: mistakes that cost marks
Kidney injury workups lose points before the reasoning is read when no baseline creatinine is given. Find one and date it. Another common gap is listing causes without the prerenal, intrinsic and postrenal frame. Sort them. Writers also forget medications that worsen injury, such as ACE inhibitors, diuretics and NSAIDs. Hold them and say when they restart. Avoid interpreting urine sodium while she is on a diuretic without noting the limitation. Record orthostatic signs and mucous membranes for volume. Keep creatinine values and dates consistent. Close with the monitoring plan and when kidney function will be rechecked. Writers also forget to record urine output, which feeds KDIGO staging along with creatinine. Add it. Another frequent slip is restarting the ACE inhibitor too early. Set conditions for restarting.
Get a NRNP 6566 Week 7 example written to your instructions
Give the desk your Week 7 prompt, the rubric and any laboratory set your section attached, and an acute kidney injury workup returns sorted by compartment on a comparable composite case. The first one carries no fee and is back in 24 to 48 hours. Values in the example were set for teaching and describe no living patient.
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NRNP 6566 Week 7 questions, answered
Why does the workup start with the baseline creatinine?
Because the injury is defined by change, and change needs a starting point. The example states where its baseline came from and how old that value is, then stages the injury against it. When no prior value exists, the example says so and explains the assumption used instead, which graders tend to reward more than a baseline quietly invented.
Does the example give fluid volumes or rates?
No. The plan explains why a volume strategy was chosen for the leading compartment and what would show it working, without specifying amounts, rates or products. Those are prescribing decisions that sit with the treating team and your course materials. The page describes the reasoning a graded workup documents, not a regimen for a patient.
What if the case has more than one cause?
The example allows for that explicitly. It names the leading compartment and keeps a second contributor open, since vomiting and a medication effect can act together. A plan built only around the leading cause tends to lose the evaluation marks, and the sample's plan carries a line for the alternative so the reasoning stays complete.
Where can I find a free NRNP 6566 Week 7 sample paper?
The diarrhea-related kidney injury workup is shown here with the baseline, KDIGO staging, the three compartments and medications as a plan category.
What stage is the kidney injury in NRNP 6566 Week 7?
KDIGO stage 2, since creatinine rose from 0.9 to 2.3 mg/dL after days of diarrhea.